Article

RevPert: ranking candidate drivers of transcriptomic state transitions via gallery-native reverse perturbation

2026-08-24

Abstract excerpt

Cellular state transitions underlie adaptation, ageing and disease, yet prioritizing catalogued genetic perturbations whose expression signatures match an observed transcriptomic shift remains difficult. Most models predict phenotype from a nominated intervention, whereas genetic inverse benchmarks are largely restricted to within-screen identity recovery. Here we introduce RevPert, a gallery-native reverse pertur...

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Literature Corpus work: 4f33b7ce-6afb-57da-a094-99ae5b3af619
DOI: 10.64898/2026.08.19.745674

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