Article

Cell-Level Virtual Screening

2026-05-13

Abstract excerpt

Virtual screening methods prioritize therapeutic candidates by predicting molecular properties and interactions. However, molecular models are insufficient to predict higher-order effects that arise in real biological systems, leading to late-stage failures in drug discovery. Virtual cells have been posed as a solution to this problem by predicting gene expression responses to drugs, but they remain weakly validat...

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Literature Corpus work: ac08a540-224f-5efc-9e93-d765dca56398
DOI: 10.64898/2026.05.11.724149

Open publication

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