Article

Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity

2022-02-10

Abstract excerpt

Adaptive immune repertoires are composed by the ensemble of B and T cell receptors (BCR, TCR) within an individual and reflect both past and current immune responses. Recent advances in single-cell sequencing enable recovery of the complete adaptive immune receptor sequences in addition to transcriptional information. Such high-dimensional datasets enable the molecular quantification of clonal selection of B and T...

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Literature Corpus work: 4efc5a1b-214b-51c0-b263-60e26ef3301b
DOI: 10.1101/2022.02.07.479381

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