Article

Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes

2020-11-10

Abstract excerpt

High-throughput single-cell sequencing (scSeq) technologies are revolutionizing the ability to molecularly profile B and T lymphocytes by offering the opportunity to simultaneously obtain information on adaptive immune receptor repertoires (VDJ repertoires) and transcriptomes. An integrated quantification of immune repertoire parameters such as germline gene usage, clonal expansion, somatic hypermutation and trans...

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Literature Corpus work: a182161c-5e1d-5b37-a32d-bdf339e4fb0b
DOI: 10.1101/2020.11.09.374280

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