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Single cell based high-throughput Ig and TCR repertoire sequencing analysis in rhesus macaques

2021-08-17

Abstract excerpt

Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired heavy- and light-chains of immunoglobulins (Ig) and VDJ- and VJ-chains of T cell receptors (TCR) from thousands of single cells simultaneously in humans and mice. Despite rhesus macaques being one of the most well-studied model organisms for the human adaptive immune response, high-throughput single cel...

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Literature Corpus work
750d10a6-bbb3-5c8c-99b7-5a5cc9ad28d6
DOI
10.1101/2021.08.17.456682
Open publication

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Single cell based high-throughput Ig and TCR repertoire sequencing analysis in rhesus macaquesDOI 10.1101/2021.08.17.456682
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