Article

TRIM58 downregulation maintains stemness via MYH9-GRK3-Hippo/YAP axis activation in triple-negative breast cancer stem cells

2023-09-14

Abstract excerpt

<title>Abstract</title> <p>Background TRIM58 is, a member of the TRIM protein family, which possess with E3 ubiquitin ligase activities. Studies have revealed that weak expression of TRIM58 plays key roles, has been implicated in the tumor progression of tumor formation due to its reduced expression. However, its role in regulating the stemness of breast cancer stem cells (CSCs) remains unexplored. Methods The...

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Literature Corpus work: 4eedd564-d64a-5354-b619-f8d3c61e5761
DOI: 10.21203/rs.3.rs-3335924/v1

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