TRIM3 Facilitates Estrogen Signaling and Modulates Breast Cancer Cell Progression

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Breast cancer ranks NO.1 in women cancer incidence worldwide, while 70% of breast cancers are estrogen receptor (ER) alpha positive. Compared with ER alpha negative breast cancer, which is more aggressive and shorter prognosis, ER alpha positive breast cancer could be well-controlled by endocrine therapy. Most of ER alpha positive breast cancer patients could be...

Topics

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• Cancer Mechanisms and Therapy
• Cytokine Signaling Pathways and Interactions
• Cytomegalovirus and herpesvirus research
• interferon and immune responses
• Peptidase Inhibition and Analysis
• RNA and protein synthesis mechanisms
• Ubiquitin and proteasome pathways
• Viral-associated cancers and disorders

Identifiers and source

Literature Corpus work

87d53eab-9130-5c32-9af6-bad97f5994ce

DOI

10.21203/rs.3.rs-709377/v1