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Article

The complexity of TRIM28 contribution to cancer

29 Aug 2017

Abstract excerpt

Since the first discovery in 1996, the engagement of TRIM28 in distinct aspects of cellular biology has been extensively studied resulting in identification of a complex nature of TRIM28 protein. In this review, we summarize core biological functions of TRIM28 that emerge from TRIM28 multi-domain structure and possessed enzymatic activities. Moreover, we will discuss whether the complexity of TRIM28 engagement in...

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PMID: 28851455
DOI: 10.1186/s12929-017-0374-4

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