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TRIM59 overexpression correlates with poor prognosis and contributes to breast cancer progression through AKT signaling pathway

3 Sept 2018

Abstract excerpt

TRIM59 has been recently implicated in the carcinogenesis of several cancers such as lung cancer, gastric cancer, and bladder cancer. However, its expression pattern and clinical significance has not been investigated in human breast cancer. In the present study, we examined TRIM59 protein expression in 95 cases of breast cancer tissues using immunohistochemistry. We found that TRIM59 was upregulated in 42 out of...

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Cancer Mechanisms and Therapy
Cytomegalovirus and herpesvirus research
interferon and immune responses

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PMID: 30175868
DOI: 10.1002/mc.22897

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