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Article

SGCE Promotes Breast Cancer Stem Cells by Stabilizing EGFR

8 Jun 2020

Abstract excerpt

Abstract Breast cancer stem cells (BCSCs) are responsible for resistance to chemotherapy, high degree of metastasis, and poor prognosis, especially in triple‐negative breast cancer (TNBC). The CD24lowCD44high and high aldehyde dehydrogenase 1 (ALDH1) cell subpopulation (CD24lowCD44high ALDH1+) exhibit very high tumor initiating capacity. In the current study, the upregulated genes are analyzed in both...

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Identifiers

PMID: 32714745
DOI: 10.1002/advs.201903700

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