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Translational control of methionine and serine metabolic pathways underpin the paralog-specific phenotypes of Rpl22 ribosomal protein mutants in cell division and replicative longevity

2020-02-06

Abstract excerpt

<h4>ABSTRACT</h4> A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Some may reflect general effects due to lower growth rate and ribosome levels, but a number of diverse phenotypes cannot be explained through this mechanism. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 6...

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Literature Corpus work
4ee5b15e-92bf-589d-b3c2-2b3ce893b700
DOI
10.1101/2020.02.05.935726
Open publication

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Translational control of methionine and serine metabolic pathways underpin the paralog-specific phenotypes of Rpl22 ribosomal protein mutants in cell division and replicative longevityDOI 10.1101/2020.02.05.935726
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