Article

Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

2024-04-20

Abstract excerpt

<h4>ABSTRACT</h4> The interplay between ribosomal protein composition and mitochondrial function is essential for sustaining energy homeostasis. Precise stoichiometric production of ribosomal proteins is crucial to maximize protein synthesis efficiency while reducing the energy costs to the cell. However, the impact of this balance on mitochondrial ATP generation, morphology and function remains unclear. Particul...

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Literature Corpus work: 9d6e7949-ea09-5553-bd13-a34fd66b6be7
DOI: 10.1101/2024.04.16.589775

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