Article

RNA degradation by ribonuclease T2 is required for phosphate homeostasis in <i>S. cerevisiae</i>

2026-07-21

Abstract excerpt

Inorganic phosphate (P i ) is a critical building block for key biomolecules including ATP, DNA, RNA, and phospholipids. Consequently, cells monitor phosphate levels and acquire phosphate when intracellular levels become low. Here we demonstrate an unanticipated connection between the enzymatic activity of the S. cerevisiae RNase T2 ortholog, Rny1, and inorganic phosphate availability. Rny1 has been studied for...

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Literature Corpus work: 26cd81e7-2552-51c7-b12a-90f9233f592f
DOI: 10.64898/2026.07.20.739639

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