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Article

Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.

Molecular and cellular biology - 1 Mar 2014

Laor Dana, Cohen Adiel, Pasmanik-Chor Metsada, Oron-Karni Varda, Kupiec Martin, Weisman Ronit

Abstract excerpt

TOR proteins reside in two distinct complexes, TOR complexes 1 and 2 (TORC1 and TORC2), that are central for the regulation of cellular growth, proliferation, and survival. TOR is also the target for the immunosuppressive and anticancer drug rapamycin. In Schizosaccharomyces pombe, disruption of the TSC complex, mutations in which can lead to the tuberous sclerosis syndrome in humans, results in a...

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Identifiers

PMID: 24344203
DOI: 10.1128/MCB.01473-13
PMCID: PMC4023818

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Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.PMID 24344203Read ↗

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Opposite Effects of Tor1 and Tor2 on Nitrogen Starvation Responses in Fission YeastSemantic proximity Read ↗

Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic defects in SAPK signalling, chromatin regulation, vesicle transport and CoA-related lipid metabolism are rescued by rapamycin in fission yeast.Semantic proximity Read ↗

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