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Inhibiting ribosome assembly and ribosome translation have distinctly different effects on the abundance and paralogue composition of ribosomal protein mRNAs in <i>Saccharomyces cerevisiae</i>

2022-11-10

Abstract excerpt

Many mutations in genes for ribosomal proteins and assembly factors cause cell stress and altered cell fate resulting in congenital diseases, collectively called ribosomopathies. Even though all such mutations depress the cell’s protein synthesis capacity, they generate many different phenotypes, suggesting that the diseases are not due simply to insufficient protein synthesis capacity. To learn more, we have inve...

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Literature Corpus work
2c3532bf-5315-5915-8efa-e20313e48aba
DOI
10.1101/2022.11.09.515899
Open publication

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Inhibiting ribosome assembly and ribosome translation have distinctly different effects on the abundance and paralogue composition of ribosomal protein mRNAs in <i>Saccharomyces cerevisiae</i>DOI 10.1101/2022.11.09.515899
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