Article
System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae.
Genetics - 1 Jan 2011
Gresham David, Boer Viktor M, Caudy Amy, Ziv Naomi, Brandt Nathan J, Storey John D, Botstein David
Abstract excerpt
An essential property of all cells is the ability to exit from active cell division and persist in a quiescent state. For single-celled microbes this primarily occurs in response to nutrient deprivation. We studied the genetic requirements for survival of Saccharomyces cerevisiae when starved for either of two nutrients: phosphate or leucine. We measured the survival of nearly all nonessential haploid null yeast...
Topics
- Genes, Fungal
- Leucine
- Mutation
- Phosphates
- Saccharomyces cerevisiae
- Sequence Analysis, DNA
- Systems Biology