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Uncharacterized yeast gene <i>YBR238C,</i> an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via <i>HAP4</i> - and <i>RMD9</i> -dependent mechanisms

2023-07-05

Abstract excerpt

Uncovering the regulators of cellular aging will unravel the complexity of aging biology and identify potential therapeutic interventions to delay the onset and progress of chronic, aging-related diseases. In this work, we systematically compared gene sets involved in regulating the lifespan of Saccharomyces cerevisiae (a powerful model organism to study the cellular aging of humans) and those with expression cha...

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Identifiers and source

Literature Corpus work
95420157-beba-5707-af76-c1bb06fc1080
DOI
10.1101/2023.07.04.547743
Open publication

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Uncharacterized yeast gene <i>YBR238C,</i> an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via <i>HAP4</i> - and <i>RMD9</i> -dependent mechanismsDOI 10.1101/2023.07.04.547743
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