Article

Structure of human RNA Polymerase III

2020-06-29

Abstract excerpt

<h4>ABSTRACT</h4> In eukaryotes, RNA Polymerase (Pol) III is the enzyme specialised for the transcription of the entire pool of tRNAs and several other short, essential, untranslated RNAs. Pol III is a critical determinant of cellular growth and lifespan across the eukaryotic kingdom. Upregulation of Pol III transcription is often observed in cancer cells and causative Pol III mutations have been described in pat...

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Literature Corpus work: 4ea14609-b9b4-510c-b2a7-1f370f3bb39b
DOI: 10.1101/2020.06.29.177279

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