Article

CSDE1 is a Post-Transcriptional Regulator of the LDL Receptor

2020-08-04

Abstract excerpt

The low-density lipoprotein receptor (LDLR) controls cellular delivery of cholesterol and clears LDL from the bloodstream, protecting against atherosclerotic heart disease, the leading cause of death in the United States. We therefore sought to identify regulators of the LDLR beyond the targets of current clinical therapies and known causes of familial hypercholesterolemia. We show that Cold Shock Domain-Containin...

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Literature Corpus work: 4d6508f9-0b85-51f1-89c7-c51578d1743e
DOI: 10.1101/2020.08.03.235028

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