Article

Unveiling the temporal impact: Exploring dynamic changes in the paediatric solid tumour immune microenvironment through time

2025-10-07

Abstract excerpt

The composition of the tumour immune microenvironment (TIME) influences tumour evolution and responsiveness to immunotherapy. While longitudinal changes in TIME have been well-characterized in adult cancers, its dynamics in childhood cancers remain poorly documented, limiting our ability to predict treatment responses and tailor immunotherapeutic strategies. This study aimed to evaluate the plasticity of TIME in p...

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Literature Corpus work: 4d0e4fdc-6ae1-59f1-8d6f-d3ac578bcd94
DOI: 10.1101/2025.10.07.680325

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