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Systems-level immunomonitoring in children with solid tumors to enable precision medicine

20 Jan 2025

Abstract excerpt

Cancer is the leading cause of death from disease in children. Survival depends not only on surgery, cytostatic drugs, and radiation but also on systemic immune responses. Factors influencing these immune responses in children of different ages and tumor types are unknown. Novel immunotherapies can enhance anti-tumor immune responses, but few children have benefited, and markers of effective responses are...

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PMID: 39837329
DOI: 10.1016/j.cell.2024.12.014

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