Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

7 Sept 2023

Abstract excerpt

BACKGROUND: Cancer immunotherapies including immune checkpoint inhibitors and Chimeric Antigen Receptor (CAR) T-cell therapy have shown variable response rates in paediatric patients highlighting the need to establish robust biomarkers for patient selection. While the tumour microenvironment in adults has been widely studied to delineate determinants of immune response, the immune composition of paediatric solid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37679810
DOI: 10.1186/s13073-023-01219-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumoursPMID 37679810Read ↗

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.Semantic proximity Read ↗

Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.Semantic proximity Read ↗

Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressureSemantic proximity Read ↗

The Immune landscape of pediatric solid tumorsSemantic proximity Read ↗

Immuno-oncologic profiling of pediatric brain tumors reveals major clinical significance of the tumor immune microenvironment.Semantic proximity Read ↗

Immune profiling of pediatric germ cell tumors identifies key cell populations and novel therapeutic targetsSemantic proximity Read ↗

The Growing Relevance of Immunoregulation in Pediatric Brain TumorsSemantic proximity Read ↗

Immuno-oncologic profiling of pediatric CNS tumors reveals major clinical significance of the tumor immune microenvironmentSemantic proximity Read ↗

Immuno-transcriptomic profiling of extracranial pediatric solid malignanciesSemantic proximity Read ↗

Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.Semantic proximity Read ↗

The T cell receptor landscape of childhood brain tumorsSemantic proximity Read ↗

Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.