Integrated Genomic Analysis of Mitochondrial RNA Processing in Human Cancers

Abstract excerpt

Alterations to mitochondrial function and mutations in mitochondrial genes have been reported for a wide variety of cancers, however the mitochondrial transcriptome remains largely unexplored in cancer despite an emerging appreciation of the role that post-transcriptional regulation plays in the etiology of these diseases. Here, we quantify and assess changes to mitochondrial RNA processing in human cancers using...

Topics

Open a Topic to create a Post that cites this publication.

• Cell Cycle
• DNA Copy Number Variations
• DNA Repair
• Genome, Human
• Genome, Mitochondrial
• Oxidative Phosphorylation
• Sequence Analysis, RNA
• Whole Genome Sequencing

Identifiers and source

Literature Corpus work

4ca8f621-a531-5a4c-b710-26a47597f29c

DOI

10.1101/080820