Article

Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers

2017-07-09

Abstract excerpt

Mitochondria are essential cellular organelles that play critical roles in cancer development. Through International Cancer Genome Consortium, we performed a multidimensional characterization of mitochondrial genomes using the whole-genome sequencing data of ~2,700 patients across 37 cancer types and related RNA-sequencing data. Our analysis presents the most definitive mutational landscape of mitochondrial genome...

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Literature Corpus work: 44e9fd08-245d-5bab-8d61-551c907b6c4b
DOI: 10.1101/161356

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