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Innate lymphoid cells: from border protection to the initiation of inflammatory diseases

29 Jan 2013

Abstract excerpt

Innate lymphoid cells (ILC) are a recently discovered group of innate lymphocytes found at mucosal surfaces. The transcriptional and effector programs of ILC strikingly resemble those of the various T-helper (Th) cell fates (that is, Th1, Th2, Th9, Th17, Th22). ILC are involved in protecting the mucosal borders by producing tissue protective factors. More recently, evidence has been provided that inappropriately...

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PMID: 23357882
DOI: 10.1038/icb.2013.3

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