Article

The sequence context of RG/RGG motifs determines condensate formation, transportin-1 binding and chaperoning

2026-01-26

Abstract excerpt

<h4>ABSTRACT</h4> Intrinsically disordered arginine-glycine-rich (RG/RGG) regions are highly abundant in the eukaryotic proteome. Proteins containing these motifs participate in fundamental cellular processes, including nuclear import, transcriptional regulation, biomolecular condensate formation, and apoptosis. Mutations or dysfunction of RG/RGG proteins have been implicated in neurodegenerative diseases and can...

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Literature Corpus work: 4bd5daa9-e49b-5753-9e5b-9ab43ebb697f
DOI: 10.64898/2026.01.26.701751

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