Article

Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase

2025-06-18

Abstract excerpt

<title>Abstract</title> <p>Stress granules (SGs) are dynamic ribonucleoprotein condensates whose assembly is driven by multivalent interactions and liquid-liquid phase separation (LLPS) of their component proteins and mRNAs. Related to multiple diseases, SGs are an ideal prototype to study cellular condensates. Understanding their regulatory factors and developing modulation methods are critical to therapeutic de...

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Literature Corpus work: 3ed382af-71a4-537a-977a-455ce7c03b12
DOI: 10.21203/rs.3.rs-6750567/v1

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