Article

Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice

2023-04-25

Abstract excerpt

<h4>Objective</h4> Glycolytic inhibition via 2-deoxy-D-glucose (2DG) has potential therapeutic benefits for a range of diseases, including cancer, epilepsy, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA), and COVID-19, but the systemic effects of 2DG on gene function across different tissues are unclear. <h4>Methods</h4> This study analyzed the transcriptional profiles of nine tissues from C57...

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Literature Corpus work: 4bb1a9b0-3c4f-564a-8bd1-d9b4a98805e4
DOI: 10.1101/2023.04.24.537717

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