Article

Multiomics Personalized Network Analyses Highlight Progressive Immune Disruption of Central Metabolism Associated with COVID-19 Severity

2021-12-17

Abstract excerpt

The system-wide metabolomics profile in COVID-19 patients identified several biomarkers that shed mechanistic insights into how SARS-CoV-2 infection is associated with gender, age, ethnicity, and co-morbidities. However, the clinical outcome and disease severity are heterogenous and cannot explain by a single factor. In this study, we used system-wide network-based system biology analysis using whole blood RNA-seq...

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Literature Corpus work: a9695786-069c-5d22-a13a-bacf3b83cab7
DOI: 10.2139/ssrn.3988390

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