Article

Tumor Cytokine-Induced Hepatic Gluconeogenesis Contributes to Cancer Cachexia: Insights from Full Body Single Nuclei Sequencing

2023-05-18

Abstract excerpt

<h4>Summary</h4> A primary cause of death in cancer patients is cachexia, a wasting syndrome attributed to tumor-induced metabolic dysregulation. Despite the major impact of cachexia on the treatment, quality of life, and survival of cancer patients, relatively little is known about the underlying pathogenic mechanisms. Hyperglycemia detected in glucose tolerance test is one of the earliest metabolic abnormalitie...

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Literature Corpus work: 4430d6c2-184e-5caf-8c65-8e03dc26b4af
DOI: 10.1101/2023.05.15.540823

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