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The metabolic footprint of aging in mice

31 Oct 2011

Abstract excerpt

Aging is characterized by a general decline in cellular function, which ultimately will affect whole body homeostasis. Although DNA damage and oxidative stress all contribute to aging, metabolic dysfunction is a common hallmark of aging at least in invertebrates. Since a comprehensive overview of metabolic changes in otherwise healthy aging mammals is lacking, we here compared metabolic parameters of young and 2...

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PMID: 22355651
DOI: 10.1038/srep00134

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