Article

NuclearIDTracker resolves intestinal cell identity and lineage dynamics through nuclear phenotypic signatures

2026-08-27

Abstract excerpt

Organoid models have transformed our understanding of intestinal renewal. Fluorescent imaging has been extensively used to identify key cell types and their differentiation pathways, but immunofluorescence provides only static readouts, whereas live imaging requires fluorescent-reporter engineering and is constrained by limited multiplexing and spectral overlap. Here, we introduce NuclearIDTracker, an explainable...

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Literature Corpus work: 4b64627c-29ab-5549-9e5d-39e9f651d509
DOI: 10.64898/2026.08.26.747251

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