Article
A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development
7 Apr 2023
Abstract excerpt
The specialized cell types of the mucociliary epithelium (MCE) lining the respiratory tract enable continuous airway clearing, with its defects leading to chronic respiratory diseases. The molecular mechanisms driving cell fate acquisition and temporal specialization during mucociliary epithelial development remain largely unknown. Here, we profile the developing Xenopus MCE from pluripotent to mature stages by...
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