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Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine

6 Mar 2018

Abstract excerpt

Innate lymphoid cells (ILCs) are abundant in mucosal tissues and involved in tissue homeostasis and barrier function. Although several ILC subsets have been identified, it is unknown if additional heterogeneity exists, and their differentiation pathways remain largely unclear. We applied mass cytometry to analyze ILCs in the human fetal intestine and distinguished 34 distinct clusters through a t-SNE–based...

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PMID: 29511064
DOI: 10.1084/jem.20171934

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