Article

A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals non-hierarchical model of development

2023-01-03

Abstract excerpt

The specialized cell-types of the mucociliary epithelium (MCE) lining the respiratory tract enable continuous airway clearing, with its defects leading to chronic respiratory diseases. The molecular mechanisms driving cell-fate acquisition and temporal specialization during mucociliary epithelial development remain largely unknown. Here, we profile the developing Xenopus MCE from pluripotent to mature stages by s...

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Literature Corpus work: 1c790ffb-353d-5c3a-8952-069095b79ce6
DOI: 10.1101/2023.01.03.521555

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