Article

Bacterial purine metabolism modulates <i>C. elegans</i> development and stress tolerance via DAF-16 translocation

2023-09-18

Abstract excerpt

Purine homeostasis is crucial for cellular function and is a conserved metabolic network from prokaryotes to humans. While extensively studied in microorganisms like yeast and bacteria, the impact of perturbed dietary purine levels on animal development and balanced growth remains poorly understood. To investigate the mechanisms underlying this deficiency, we utilized Caenorhabditis elegans as the metazoan model....

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Literature Corpus work: 4b3adace-df85-544b-ace5-fc6bf8339162
DOI: 10.1101/2023.09.17.558182

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