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Adenylosuccinate Lyase activity in the Purine recycling pathway is essential for developmental timing, germline maintenance and muscle integrity in <i>C. elegans</i>

2018-03-07

Abstract excerpt

Purine homeostasis is ensured through a metabolic network widely conserved from prokaryotes to humans. Purines can either be synthesized de novo , reused, or produced by interconversion of extant metabolites using the so-called recycling pathway. Although thoroughly characterized in microorganisms, such as yeast or bacteria, little is known about the regulation of this biosynthesis network in metazoans. In humans...

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Literature Corpus work
a30cee9e-b41f-57b1-b591-95c4bb151122
DOI
10.1101/277640
Open publication

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