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Article

Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut.

Current biology : CB - 21 Jun 2021

Zhang Fan, Weckhorst Jessica L, Assié Adrien, Hosea Ciara, Ayoub Christopher A, Khodakova Anastasia S, Cabrera Mario Loeza, Vidal Vilchis Daniela, Félix Marie-Anne, Samuel Buck S

Abstract excerpt

Host genetic landscapes can shape microbiome assembly in the animal gut by contributing to the establishment of distinct physiological environments. However, the genetic determinants contributing to the stability and variation of these microbiome types remain largely undefined. Here, we use the free-living nematode Caenorhabditis elegans to identify natural genetic variation among wild strains of C. elegans that...

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PMID: 34048707
DOI: 10.1016/j.cub.2021.04.046
PMCID: PMC8222194

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