Article

Chemoenzymatic Synthesis of 6-Sulfo Sialyl Lewis <sup>x</sup> Containing Glycans to Probe the Receptor Specificity of MERS Coronavirus

2026-08-07

Abstract excerpt

<h4>ABSTRACT</h4> The initial attachment of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) to host cell sialosides is critical for infection, yet its precise receptor specificity remains poorly understood. Here, we describe a chemoenzymatic methodology to synthesize a comprehensive panel of 6-sulfo sialyl Lewis x (6-sulfo-SLe x ) containing glycans. Our approach entails the enzymatic assembly of an oli...

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Literature Corpus work: 4a5d3c4c-de9b-5615-bad4-510999fbfb15
DOI: 10.64898/2026.08.06.743223

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Chemoenzymatic Synthesis of 6-Sulfo Sialyl Lewis <sup>x</sup> Containing Glycans to Probe the Receptor Specificity of MERS CoronavirusDOI 10.64898/2026.08.06.743223Read

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