Article

Dexamethasone modulate TWIST mediated EndMT changes in venous EC under acute shear stress. Implications for vein grafts disease

2023-06-05

Abstract excerpt

<h4>Background</h4> The use of vein grafts in coronary artery surgery is complicated by a high late restenosis rate resulting from the development of intimal hyperplasia, and accelerated atherosclerosis. TGFβ has been implicated in the process of intimal hyperplasia but the role of TGFβ driven Endothelial to mesenchymal is not fully understood. Here, we have investigated the hypothesis that arterial shear stress (...

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Literature Corpus work: 4a4a0b62-36c3-561a-bf45-16e2a58dd85a
DOI: 10.1101/2023.05.26.23290570

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Dexamethasone modulate TWIST mediated EndMT changes in venous EC under acute shear stress. Implications for vein grafts diseaseDOI 10.1101/2023.05.26.23290570Read

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