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Article

Atheroprone flow enhances the endothelial-to-mesenchymal transition

27 Jul 2018

Abstract excerpt

The endothelial-to-mesenchymal transition (EndoMT) is a cellular process featuring decreased expression of endothelial marker genes but increased expression of mesenchymal marker genes. The EndoMT is involved in endothelial dysfunction and the pathogenesis of atherosclerosis. To investigate the dynamic expression of EndoMT genes in vascular endothelial cells under atheroprotective pulsatile shear stress (PS) and...

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PMID: 30052471
DOI: 10.1152/ajpheart.00213.2018

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