Article

FAK- and TGF-β1-dependent biomechanical alterations in microvascular endothelial cells exposed to spatial fluid shear stress gradients

2026-06-26

Abstract excerpt

<title>Abstract</title> <p>Endothelial cells (EC) form a dynamic monolayer barrier that regulates vascular permeability and is highly sensitive to mechanical cues, including shear stress (SS) generated by blood flow. While spatial shear stress gradients (SSG) are strongly linked to vascular pathologies such as atherosclerosis, their direct effects on EC kinematics, mechanics, and signaling, and whether these resp...

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Literature Corpus work: 69aec4bc-167b-5a55-9b7d-a9e956222e29
DOI: 10.21203/rs.3.rs-9507974/v1

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