Article

Genetically predicted on-statin LDL response is associated with higher intracerebral hemorrhage risk

2022-03-23

Abstract excerpt

Statins lower low-density lipoprotein (LDL) cholesterol and are widely used for the prevention of atherosclerotic cardiovascular disease. Whether statin-induced LDL reduction increases risk of intracerebral hemorrhage (ICH) has been debated for almost two decades. Here, we explored whether genetically predicted on-statin LDL response is associated with ICH risk using Mendelian Randomization. Utilizing genomic data...

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Literature Corpus work: 4a2275ad-de2d-57e8-88f2-071f78857323
DOI: 10.1101/2022.03.22.22272697

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