Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LDL-c Lowering, Ischemic Stroke, and Small Vessel Disease Brain Imaging Biomarkers: A Mendelian Randomization Study

4 Apr 2024

Abstract excerpt

BACKGROUND: The effects of lipid-lowering drug targets on different ischemic stroke subtypes are not fully understood. We aimed to explore the mechanisms by which lipid-lowering drug targets differentially affect the risk of ischemic stroke subtypes and their underlying pathophysiology. METHODS: Using a 2-sample Mendelian randomization approach, we assessed the effects of genetically proxied low-density...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebrovascular and Carotid Artery Diseases
Share to Dementia and Cognitive Impairment Research
Share to Moyamoya disease diagnosis and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38572634
DOI: 10.1161/strokeaha.123.045297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LDL-c Lowering, Ischemic Stroke, and Small Vessel Disease Brain Imaging Biomarkers: A Mendelian Randomization StudyPMID 38572634Read ↗

Lipids, Apolipoproteins, Lipid-Lowering Drugs, and the Risk of Cerebral Small Vessel Disease: A Mendelian Randomization Study.Semantic proximity Read ↗

Genetic determinants of circulating metabolites and the risk of stroke and its subtypes.Semantic proximity Read ↗

Optimizing treatment of cardiovascular risk factors in cerebral small vessel disease using geneticsSemantic proximity Read ↗

Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.Semantic proximity Read ↗

Lipids, Apolipoproteins, Statins, and Intracerebral Hemorrhage: A Mendelian Randomization StudySemantic proximity Read ↗

Genetically predicted small dense low-density lipoprotein cholesterol and ischemic stroke subtype: multivariable Mendelian randomization study.Semantic proximity Read ↗

Mendelian Randomization in Stroke: A Powerful Approach to Causal Inference and Drug Target ValidationSemantic proximity Read ↗

Genetic downregulation of interleukin-6 signaling and arteriolosclerotic cerebral small vessel disease: a drug target Mendelian randomization analysisSemantic proximity Read ↗

Causal role of lipid metabolome on the risk of ischemic stroke, its etiological subtypes, and long-term outcome: A Mendelian randomization study.Semantic proximity Read ↗

Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes: A Mendelian Randomization Study.Semantic proximity Read ↗

Genetically predicted on-statin LDL response is associated with higher intracerebral hemorrhage riskSemantic proximity Read ↗

Mendelian Randomization Studies in Stroke: Exploration of Risk Factors and Drug Targets With Human Genetic Data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.