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Article

Association of Polygenic Susceptibility to Hyperlipidemia With Cholesterol Control and Recurrent Stroke in Ischemic Stroke Survivors.

Neurology - 9 Sept 2025

Wu Kane, Huo Shufan, Rivier Cyprien A, Torres-Lopez Victor, Sharma Richa, de Havenon Adam, Worrall Bradford B, Sheth Kevin Navin, Falcone Guido J

Abstract excerpt

BACKGROUND AND OBJECTIVES: Common genetic variation significantly influences the risk of stroke, and previous research has indicated that polygenic susceptibility to hypertension and diabetes negatively affects the clinical trajectory of ischemic stroke survivors. We hypothesize that polygenic susceptibility to hyperlipidemia (PSH) negatively affects cholesterol control in this same population. METHODS: We...

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Identifiers

PMID: 40825160
DOI: 10.1212/WNL.0000000000213966
PMCID: PMC13014709

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