Article
Prostate cancer risk prediction using a polygenic risk score.
Scientific reports - 13 Oct 2020
Sipeky Csilla, Talala Kirsi M, Tammela Teuvo L J, Taari Kimmo, Auvinen Anssi, Schleutker Johanna
Abstract excerpt
Hereditary factors have a strong influence on prostate cancer (PC) risk and poorer outcomes, thus stratification by genetic factors addresses a critical need for targeted PC screening and risk-adapted follow-up. In this Finnish population-based retrospective study 2283 clinically diagnosed and 455 screen-detected patients from the Finnish Randomised Study of Screening for Prostate Cancer (FinRSPC), 2400 healthy...
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