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Development and validation of a simple prostate cancer risk prediction model based on age, family history, and polygenic risk.

The Prostate - 1 Jul 2023

Dite Gillian S, Spaeth Erika, Murphy Nicholas M, Allman Richard

Abstract excerpt

BACKGROUND: Accurate prostate cancer risk assessment will enable identification of men who are at increased risk of the disease. Using the UK Biobank population-based cohort, we developed and validated a simple model comprising age, family history, and a polygenic risk score (PRS) to predict 5-year risk of prostate cancer. METHODS: Eligible participants were unaffected Caucasian men aged 40-69 years at their...

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PMID: 37062910
DOI: 10.1002/pros.24537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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