Article

Mitochondrial genome editing: a possible interplay of atherosclerosis-associated mutation m.15059G>A with defective mitophagy

2023-04-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> It was assumed that the cause of chronic inflammation in atherosclerosis is a disturbance of the innate immunity response, caused, among other factors, by mitochondrial dysfunctions. It was also suggested that mitochondrial dysfunction may be caused by heteroplasmic mutations in mitochondrial DNA. The aim of this study was to evaluate the effect of the mitochondrial nonsense...

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Literature Corpus work: 4993b7b9-eac0-5989-969f-d6ec97ac71e2
DOI: 10.1101/2023.04.21.537899

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