Article
Genetics of Arterial-Wall-Specific Mechanisms in Atherosclerosis: Focus on Mitochondrial Mutations.
Current atherosclerosis reports - 9 Aug 2020
Orekhov Alexander N, Ivanova Ekaterina A, Markin Alexander M, Nikiforov Nikita G, Sobenin Igor A
Abstract excerpt
PURPOSE OF REVIEW: Mutations in both nuclear and mitochondrial genes are associated with the development of atherosclerotic lesions in arteries and may provide a partial explanation to the focal nature of lesion distribution in the arterial wall. This review is aimed to discuss the genetic aspects of atherogenesis with a special focus on possible pro-atherogenic variants (mutations) of the nuclear and...
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