Article
Mitochondrion as a Selective Target for the Treatment of Atherosclerosis: Role of Mitochondrial DNA Mutations and Defective Mitophagy in the Pathogenesis of Atherosclerosis and Chronic Inflammation.
Current neuropharmacology - 1 Jan 2020
Orekhov Alexander N, Poznyak Anastasia V, Sobenin Igor A, Nikifirov Nikita N, Ivanova Ekaterina A
Abstract excerpt
BACKGROUND: Atherosclerosis is a chronic inflammatory condition that affects different arteries in the human body and often leads to severe neurological complications, such as stroke and its sequelae. Affected blood vessels develop atherosclerotic lesions in the form of focal thickening of the intimal layer, so called atherosclerotic plaques. OBJECTIVES: Despite the high priority of atherosclerosis research for...
Topics
Join the communities discussing this publication.